Insight into the neurology of Angelman syndrome

Results recently published in PLoS Biology (11, e1001478; 2013) elucidate the neurological disruptions that occur in Angelman syndrome and introduce a compound that can rescue the disruptions, restoring neural function in mice. John Marshall (Brown University, Providence, RI), senior author of the article, warned that it is too soon to tell when a clinical therapy might be available. But the results hold promise for those who have the disease.

Lab Anim. (NY) 42, 112 (2013).

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