Lyme disease, caused by the spirochete Borrelia burgdorferi, is the most prevalent arthropod-borne illness in the US. Disease severity varies greatly, with up to 60% of untreated patients developing a self-limiting, inflammatory arthritis. Even after appropriate antibiotic therapy, 10% of patients may develop chronic arthritis lasting months to years. The spectrum of arthritis severity amongContinueContinue reading “Genetic variant regulates arthritis severity”
Tag Archives: Lyme disease
Toward better management of Lyme disease
Results of a new study by researchers at Yale University School of Medicine (New Haven, CT) may point to the cause of persistent arthritis in people with Lyme disease. About 10% of Lyme sufferers will experience Lyme-related arthritis; in about 10% of these cases, the arthritis can last for months, despite antibiotic therapy. Its pathologyContinueContinue reading “Toward better management of Lyme disease”