Controlling gene expression in vivo forms the basis for genetic engineering for research and therapeutic purposes. Recently, Haifeng Ye and Martin Fussenegger (Eidgenössische Technische Hochschule Zurich, Basel, Switzerland) reported their success in developing a light-driven, synthetic biology mechanism to control transcription. To prove that the technique has therapeutic potential, they used it to control insulinContinueContinue reading “‘Switching on’ transcription”
Tag Archives: bioengineering
How geckos get sticky
The adhesion and locomotion systems of geckos have been of interest in the biological and biotechnological worlds for decades. Research has uncovered the structure of geckos’ feet and the mechanisms underlying their exceptional clinging ability. But until recently, not much was known about when and how geckos activate their traction systems. Now, Anthony P. RussellContinueContinue reading “How geckos get sticky”
Fishing for toxic bacteria
Bacterial pathogens in food and water cause more than 76 million infections per year in the US, which have symptoms ranging from mild gastrointestinal discomfort to severe illness and even death. Accurate detection of these pathogens is essential for avoiding infection. Although molecular and immunological detection methods have progressed, they do sometimes fail to identifyContinueContinue reading “Fishing for toxic bacteria”
Engineered cartilage does better under pressure
Arthritis affects millions of people worldwide, causing pain and stiffness in joints. In some cases, arthritis develops after the cartilage in a joint is damaged. Cartilage acts to cushion the joints, allowing for smooth movement. Because cartilage cannot repair itself after injury, tissue engineers have attempted to generate new cartilage that could be transplanted intoContinueContinue reading “Engineered cartilage does better under pressure”
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