Next generation of DES discussed at Stent Revolution meeting

Several presentations focusing on the safety, efficacy, and appropriate usage of emerging drug-eluting stent technologies were highlighted at the Cardiovascular Research Foundation’s “Enter the Drug-Eluting Stent Revolution V” summit, held in mid March immediately before the annual meeting of the American College of Cardiology. Proceedings of TCT 3, 7-9 (2006). view PDF

In the running with ACTN3

Researchers in Australia recently reported a polymorphism in ACTN3, encoding α-actinin-3, associated with sprint versus endurance performance among elite athletes. The report raises the idea that genetic differences, such as that in ACTN3, could be useful predictors of athletic performance at the elite level, although such potential has not been established. Nat. Genet. 35, 123ContinueContinue reading “In the running with ACTN3”

Live long and prosper

Besides the long hours, low pay and chance to wear shorts to work in December, what are the perks of being a scientist? A study in the Journal of the Royal Society of Medicine reports that students who focused on science, medicine or engineering as undergraduates have a lower risk of ‘all-cause mortality’ than thoseContinueContinue reading “Live long and prosper”

Can a virus outsmart glioma?

Glioma is a lethal brain cancer that can resist radiation and chemotherapy. Adenovirus-based treatment has been difficult, but a new viral system has now shown unprecedented success. Juan Fueyo and colleagues genetically manipulated an adenovirus to effectively destroy a tumor from the inside out. Nat. Genet. 34, 133 (2003). view full text (login required)

Wrinkle-free

Would you rather be wrinkly or bald? Researchers at Washington University in St. Louis recently described the positional cloning of a spontaneous mutation in wrinkle-free mice (wrfr), grafted skin from which is defective in hair growth. The homozygous mutant mice have extremely thick and tight skin with no wrinkles, but don’t throw out that wrinkleContinueContinue reading “Wrinkle-free”

Nutrient pulses and phytoplankton growth

In estuaries, phytoplankton are exposed to rapidly changing conditions that may have profound effects on community structure and function. In these experiments, we evaluated the growth, productivity, and compositional responses of natural phytoplankton communities exposed to limiting nutrient additions and incubation conditions typical of estuarine habitats. Mesocosm bioassays were used to measure the short-term (2-day)ContinueContinue reading “Nutrient pulses and phytoplankton growth”

Seasonal shifts in phyoplankton communities

The spatiotemporal distributions of major phytoplankton taxa were quantified to estimate the relative contribution of different microalgal groups to biomass and bloom dynamics in the eutrophic Neuse River Estuary, North Carolina, USA. Biweekly water samples and ambient physical and chemical data were examined at sites along a salinity gradient from January 1994 through December 1996.ContinueContinue reading “Seasonal shifts in phyoplankton communities”