Jorge Ferreira [Public domain] via Wikimedia CommonsThe development of drug resistance is a primary factor in the failure of malaria treatment strategies. For example, artemisinin is the drug most commonly used to treat human malaria worldwide, but some malaria parasites have developed resistance to it. Overcoming the development of resistance is therefore a key objective in the search for improved malaria treatments. Researchers recently showed that treatment with the whole plant (Artemisia annua) from which artemisinin is derived could overcome existing resistance to artemisinin in a rodent malaria parasite.