PFO closure for migraines remains an open question

Though greatly anticipated, results of the MIST (Migraine Intervention with STARFlex Technology) trial, presented during the Innovation in Intervention Summit at the annual meeting of the American College of Cardiology in March 2006, failed to prove the benefits of patent foramen ovale (PFO) closure in migraine prevention. The MIST results add to the body of information that suggests closure may help migraine sufferers, but questions about the PFO-migraine link persist.

Proceedings of TCT 3, 7-9 (2006).

view PDF